Title Asthma patients have an increased caries rate in primary and permanent dentitions
Clinical Question For an otherwise low caries risk patient, does asthma cause increased incidence of dental caries?
Clinical Bottom Line Asthma patients have an increased caries rate in primary and permanent dentitions.
Best Evidence  
PubMed ID Author / Year Patient Group Study type
(level of evidence)
29972654Agostini /201836 studiesMeta-Analysis and Meta-regression
Key resultsAfter a thorough review of the literature, 36 clinical studies met SR criteria and were used in meta-analysis. The The Odds ratio (OR) for the pooled effect was 1.45 (95% confidence interval (CI): 1.22–1.72; I2, 71.8%; p < 0.001) and 1.52 (95% CI: 1.34–1.73; I2, 83.1%; p < 0.001). Conclusion was that asthma does affect caries rate in primary and permanent dentition.
Evidence Search "asthma" and "caries"
Comments on
The Evidence
Validity: Agostini's study is a high level meta-analysis that performed a comprehensive and detailed search of the relevant trials. It was conducted in accordance with the PRISMA guidelines and the Critical Appraisal Checklist recommended by the Joanna Briggs Institute (JBI) was adopted to assess the quality of the studies. Potential bias was ruled out using the funnel plot and Egger test and the statistical analysis was performed using the STATA 14.2 software. All of this confirms that this study was systematic, consistent and had low bias. Perspective: This analysis does provide significant evidence that asthma impacts caries experience in primary and permanent dentitions. The inclusion criteria for this study reflects the asthmatic population that general, pediatric and orthodontic practices will include, further supporting the relevance of this critical appraisal.
Applicability This evidence can be used in clinical practice to provide applicable oral health care instruction to patients being treated for asthma and parents of children and adolescents with asthma. Additionally, this information can inform practitioners of the increase in caries risk for asthmatic patients so that they can include prevention measures in treatment planning.
Specialty (Public Health) (General Dentistry) (Orthodontics) (Pediatric Dentistry) (Periodontics)
Keywords asthma, caries, physician; patient education; preventive; prevention
ID# 3328
Date of submission 10/09/2018
E-mail pagek@livemail.uthscsa.edu
Author Kara Whittington
Co-author(s) e-mail
Faculty mentor Dr. Elva Jordan, DDS
Faculty mentor e-mail jordanev@livemail.uthscsa.edu
Basic Science Rationale
(Mechanisms that may account for and/or explain the clinical question, i.e. is the answer to the clinical question consistent with basic biological, physical and/or behavioral science principles, laws and research?)
None available
Comments and Evidence-Based Updates on the CAT
None available