| Title |
Tooth Loss Is More Prevalent in Adults with Major Depressive Disorder |
| Clinical Question |
In patients with major depressive disorder is tooth loss more prevalent than in people without it?
|
| Clinical Bottom Line |
In adults with current depression, tooth loss is more prevalent than in adults without current depression. This is supported by a cross-sectional study that analyzed the association between tooth loss and current depression after adjusting for confounding factors in 80,486 adults using logistic regression analyses.
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| Best Evidence |
|
| PubMed ID |
Author / Year |
Patient Group |
Study type
(level of evidence) |
| 21883356 | Okoro/2012 | 80,486 adults in 16 states who participated in the Behavioral Risk Factor Surveillance System to evaluate current depression, lifetime diagnosis of depression, and lifetime diagnosis of anxiety. | Cross Sectional Study | | Key results | The results showed that, after adjusting for confounding factors like sociodemographic factors and the use of oral health services, the odds of being in the 1-5 missing teeth, 6-31 missing teeth, or all-teeth-missing categories versus 0 teeth removed are higher in adults with current depression than adults without depression (adjusted odds ratio [AOR] = 1.35; 95% CI=1.14–1.59; AOR = 1.83; 95% CI=1.51–2.22; and AOR = 1.44; 95% CI=1.11–1.86, respectively).
| |
| Evidence Search |
("depressive disorder"[MeSH Terms] OR ("depressive"[All Fields] AND "disorder"[All Fields]) OR "depressive disorder"[All Fields] OR "depression"[All Fields] OR "depression"[MeSH Terms]) AND ("tooth loss"[MeSH Terms] OR ("tooth"[All Fields] AND "loss"[All Fields]) OR "tooth loss"[All Fields])
|
Comments on
The Evidence |
Validity: The cross-sectional study showed significant correlations between major depressive disorder and tooth loss. There were a large number of subjects in the study, which strengthens the evidence. One thing that might be a source of bias is that the survey was only conducted in 16 states, so there might be some non-coverage bias. Also, all the data obtained for the study was done via questionnaires, which could be a source of recall or response bias.
|
| Applicability |
For patients with current depression there is a higher prevalence of tooth loss; therefore it is important to try and identify these patients and manage them appropriately to decrease the risk of tooth loss.
|
| Specialty |
(General Dentistry) (Oral Surgery) (Interprofessional CATs) |
| Keywords |
depression; tooth loss
|
| ID# |
3054 |
| Date of submission |
04/04/2016 |
| E-mail |
salinaso@livemail.uthscsa.edu |
| Author |
Omar Salinas |
| Co-author(s) |
|
| Co-author(s) e-mail |
|
| Faculty mentor |
John P. Hatch, PhD |
| Faculty mentor e-mail |
hatch@uthscsa.edu |
| |
|
Basic Science Rationale
(Mechanisms that may account for and/or explain the clinical question, i.e. is the answer to the clinical question consistent with basic biological, physical and/or behavioral science principles, laws and research?) |
| None available | |
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Comments and Evidence-Based Updates on the CAT
(FOR PRACTICING DENTISTS', FACULTY, RESIDENTS and/or STUDENTS COMMENTS ON PUBLISHED CATs) |
| None available | |