|
Title |
Evidence supports that toothpaste with arginine, calcium carbonate and fluoride is effective at treating dentin hypersensitivity |
Clinical Question |
In treating patients with dentin hypersensitivity, is there a better therapeutic treatment for reducing hypersensitivity when compared to fluoride alone? |
Clinical Bottom Line |
Toothpaste with arginine, calcium carbonate and fluoride was more effective at immediate relief of dentin hypersensitivity than fluoride alone. (See Comments on the CAT below) |
Best Evidence |
(you may view more info by clicking on the PubMed ID link) |
PubMed ID |
Author / Year |
Patient Group |
Study type
(level of evidence) |
#1) 19831165 | Nathoo/2009 | One-hundred and twenty-five subjects from the Piscataway, New Jersey, USA area who presented with two hypersensitive teeth based on tactile and air blast hypersensitivity scores. | Randomized Controlled Trial | Key results | The 8.0% arginine toothpaste group showed statistically significant (p < 0.05) reductions in dentin hypersensitivity on both tactile and air blast hypersensitivity scores immediately after direct application. Compared to the control toothpaste groups, the 8.0% arginine group showed statistically significant (p < 0.05) reductions in sensitivity after three days of twice-daily regular tooth brushing. | |
Evidence Search |
Evidence Search:SearchMost Recent QueriesTimeResult#17Search ("Dentin Sensitivity"[Mesh] AND "Dentin Desensitizing Agents"[Mesh]) AND "Therapeutics"[Mesh]23:21:255 |
Comments on
The Evidence |
This study, a RCT of 125 patients, compared treatment with a toothpaste containing 8% arginine, calcium carbonate, and 1450 ppm fluoride with toothpaste containing 1450 ppm fluoride, in patients with dentin sensitivity. Recall bias was unlikely and follow-up was good, and validity was strong because patients were similar at the start and were treated the same. |
Applicability |
The results in the best evidence can help me in my practice to be able to confidently recommend a type of desensitizing treatment for my patients. From this evidence, I will be able to say that the new toothpaste with arginine is helpful in immediately reducing pain from sensitivity. |
Specialty/Discipline |
(General Dentistry) (Dental Hygiene) |
Keywords |
|
ID# |
594 |
Date of submission: |
03/25/2010 |
E-mail |
chitwood@livemail.uthscsa.edu |
Author |
Aubrey Kendall Chitwood |
Co-author(s) |
|
Co-author(s) e-mail |
|
Faculty mentor/Co-author |
E. Penn Jackson, DDS |
Faculty mentor/Co-author e-mail |
JacksonEP@uthscsa.edu |
Basic Science Rationale
(Mechanisms that may account for and/or explain the clinical question, i.e. is the answer to the clinical question consistent with basic biological, physical and/or behavioral science principles, laws and research?) |
post a rationale |
None available | |
|
Comments and Evidence-Based Updates on the CAT
(FOR PRACTICING DENTISTS', FACULTY, RESIDENTS and/or STUDENTS COMMENTS ON PUBLISHED CATs) |
post a comment |
by David Wallach (San Antonio, TX) on 04/24/2012 I conducted a PubMed search on this topic on 4/22/2012. The information provided in this CAT appears to be up to date. It also refers to the highest level of evidence. | |
|
|