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Title Internal Root Resorption is Better Detected with Cone-Beam Computed Tomography than with Intraoral Radiography
Clinical Question Is cone-beam computed tomography more effective than intraoral radiographs in detecting internal root resorption?
Clinical Bottom Line CBCT is able to detect internal root resorption at an almost gold-standard specificity and sensitivity in in-vitro studies; however, no gold standard is applicable to in-vivo studies.
Best Evidence (you may view more info by clicking on the PubMed ID link)
PubMed ID Author / Year Patient Group Study type
(level of evidence)
#1) 19627378Patel/2009 n=5 (external); n=5 (internal); n=5 (control)Diagnostic accuracy study
Key resultsFor diagnosing internal root resorption, CBCT was found to possess sensitivity, specificity, PPV and NPV values all equal to 1.000 ± 0.000 (gold standard equivalent). Intraoral radiographs had sensitivity, specificity, PPV, and NPV values of 0.590 (0.216), 0.974 (0.064), 0.945 (0.136), and 0.713 (0.120), respectively. The kappa value for inter-examiner agreement was 0.365 and 0.925 for intraoral radiography and CBCT respectively for the diagnosis of internal resorption.
#2) 21238797Kamburoğlu/2011Extracted teeth; n=25(external); n=25 (internal); n= 40 (control)In-vitro study
Key resultsThe kappa value for intra-examiner agreement ranged between moderate (0.457–0.103) to good (0.618–0.104) for intraoral radiography and good (0.606–0.096) and excellent (0.745–0.080) for CBCT for the diagnosis of internal resorption. The kappa value for inter-examiner agreement ranged between poor (0.105–0.089) to moderate (0.516–0.118) for intraoral radiography and moderate (0.551–0.104) and good (0.754–0.073) for CBCT. For intraoral radiographs the sensitivity ranged between 0.24 to 0.6; specificity, 0.63 to 0.95; PPV, 0.37 to 0.84; and NPV, 0.75 to 0.83. For CBCT, the sensitivity ranged between 0.52 to 0.72; specificity, 0.72 to 0.98; PPV, 0.5 to 0.87; and NPV, 0.84 to 0.88.
#3) 26780040Lima/2016n=28 (external); n=8 (internal); n=20 (control)Diagnostic accuracy study
Key resultsThe accuracy of CBCT in diagnosing internal (P = 0.0038) inflammatory resorption was significantly higher than for periapical radiography. The kappa values for interobserver agreement ranged between 0.795 to 0.805 for periapical radiograph and 0.795 to 1.0 for CBCT. The kappa value for intraobserver agreement was greater than 0.8 for all examiners. CBCT had sensitivity, specificity, PPV, NPV and accuracy values of 0.938, 1.00, 1.00, 1.00 and 0.991 respectively. Periapical radiography had sensitivity, specificity, PPV, NPV and accuracy values of 0.563, 0.961, 0.690, 0.935, 0.908 and 0.0038 respectively.
Evidence Search (cone beam computed tomography [MeSH Terms]) AND dental radiography [MeSH Terms]) AND internal root resorption [MeSH Terms]
Comments on
The Evidence
Validity: The most accurate diagnostic test for internal root resorption would be extraction and subsequent histologic or scanning electron microscope analysis; however, such methods are clinically unethical. Therefore, no clinical gold standard for the diagnosis of internal root resorption currently exists. Patel and Lima’s clinical studies used the consensus of a 6- and 4-clinician panel respectively as the gold standard. As stated by Patel et al., resorptive lesions are usually of atypical size and shape. The studies above measured internal resorptive lesions of differing sizes and locations in order to determine if these variables affected sensitivity and specificity values. Perspective: A perfect gold standard for detecting internal root resorption is currently non-existent. The use of CBCT for its diagnosis shows promise as a possible gold standard in the future, although more studies must be conducted at a higher level of evidence (preferably in-vivo, as in the Patel and Lima studies). Additionally, CBCT generally exposes the patient to higher levels of radiation than conventional radiographs and therefore CBCT should be used conservatively, particularly in cases where internal root resorption is suspected but not readily detected with other radiographic techniques.
Applicability Although CBCT is readily available in most in institutional settings, access to CBCT machines in the private setting widely varies. Also, the cost associated with CBCT image capture and interpretation may be significant. Additionally, the patient must be willing to accept the additional exposure to ionizing radiation. As stated above, CBCT may be indicated in select cases where internal root resorption is suspected, but not readily seen with other methods of imaging. This would allow patients to be aware of resorptive processes and seek intervention.
Specialty/Discipline (Oral Medicine/Pathology/Radiology) (Endodontics) (General Dentistry)
Keywords Internal root resorption, Cone-beam computed tomography, CBCT
ID# 3404
Date of submission: 11/21/2019spacer
E-mail baaklini@uthscsa.edu
Author Nayla Baaklini
Co-author(s) Angela Hoikka
Co-author(s) e-mail Hoikka@uthscsa.edu
Faculty mentor/Co-author Dr. Hassem Geha
Faculty mentor/Co-author e-mail Geha@uthscsa.edu
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