ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM
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| Title |
Use of Corticosteroids Before the extraction of Third Molars to Reduce Post-Operative Edema |
| Clinical Question |
Can pre-medication with corticosteroids help in reduction of edema, following extraction of third molars? |
| Clinical Bottom Line |
Pre-medication with corticosteroids when extracting third molars allows mild-moderate reduction in edema after surgery. |
| Best Evidence |
(you may view more info by clicking on the PubMed ID link) |
| PubMed ID |
Author / Year |
Patient Group |
Study type
(level of evidence) |
| #1) 18718396 | Markiewwicz/2008 | 10 Clinical Trial Total patients 513 | Meta-Analysis, Research support (Non-US Gov) | | Key results | In this study two Treatment groups were used, One receiving Corticosteroids (245 patients) before the extraction of Third molars & the second Control group(268 patients) with no pre-medication. Patients pre-medicated with Corticosteroids before the extraction of third Molar showed 0.6 mm less swelling than controls 1 to 3 days after surgery (P<0.001) and 0.5 mm less swelling than controls 4-7 days after surgery (P=0.03). Hence concluding that Pre-medication with CS when extracting third molars allows mild to moderate reduction in Edema up to 7 days post-operatively. | |
| Evidence Search |
PubMed Search; “Corticosteroids” MeSH, “Edema” MeSH, “Third molar extractions” MeSH. “Swelling” MeSH. |
Comments on
The Evidence |
Patients represented the full spectrum of Third molar extracts studied. Criteria for the findings were explicit & credible. The diagnostic work-up was comprehensive and consistently applied. There was no mention on the Follow-up of the patients. The author was not found to have competing interests. |
| Applicability |
The study participants represented a full spectrum of Third Molar Extraction patients. The administration of Corticosteroids pre-operatively is Feasible in the surgical operatory. |
| Specialty/Discipline |
(General Dentistry) (Oral Surgery) |
| Keywords |
Corticosteroids, edema, extraction, Third Molars.
|
| ID# |
2561 |
| Date of submission: |
08/16/2013 |
| E-mail |
Faiza.Baig@ucdenver.edu |
| Author |
Faiza Baig |
| Co-author(s) |
|
| Co-author(s) e-mail |
|
| Faculty mentor/Co-author |
Ronald N. Brown, DDS |
| Faculty mentor/Co-author e-mail |
Ronald.Brown@ucdenver.edu |
Basic Science Rationale
(Mechanisms that may account for and/or explain the clinical question, i.e. is the answer to the clinical question consistent with basic biological, physical and/or behavioral science principles, laws and research?) |
post a rationale |
| None available | |
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Comments and Evidence-Based Updates on the CAT
(FOR PRACTICING DENTISTS', FACULTY, RESIDENTS and/or STUDENTS COMMENTS ON PUBLISHED CATs) |
post a comment |
| None available | |
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