ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM
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Title Light-Cured Resin-Based Sealants Have a Significantly Higher Long-Term Retention Rate than Fluoride-Containing Light-Cured Resin-Based Sealants
Clinical Question In a patient with susceptible pits and fissures, do light-cured resin-based sealants (LRBS) have a higher long-term retention rate than fluoride-containing resin-based sealants (FRBS)?
Clinical Bottom Line LRBS have a higher long-term retention rate than FRBS, and the difference in retention rates is greater as the time length is increased.
Best Evidence (you may view more info by clicking on the PubMed ID link)
PubMed ID Author / Year Patient Group Study type
(level of evidence)
#1) 22137936Kuhnisch/2012Patients with susceptible pits and fissures.Meta-analysis of clinical trials and field studies
Key resultsAt 24 months, there was not a significant difference in retention rates between LRBS and FRBS (77.8% CI: 64.3-88.9 versus 81.1% CI: 45.8-97.8, respectively). At 60 months, LRBS had a significantly higher retention rate than FRBS (83.8% CI: 54.9-94.7 versus 69.9% CI: 51.5-86.5, respectively).
#2) 16948671Muller-Bolla/2006Permanent molars in patients ≥ 5 years old.Meta-analysis of clinical trials
Key resultsAt 12 months, there was no statistical difference between LRBS and FRBS (RR = 1.01, 95% CI: 0.96 – 1.06). However, at 48 months, LRBS had a significantly higher retention rate than FRBS (RR = 0.80, 95% CI: 0.72 – 0.89).
Evidence Search "Pit and Fissure Sealants"[Mesh] AND (systematic[sb] OR Meta-Analysis[ptyp])
Comments on
The Evidence
In the Kuhnisch study, 110 clinical reports were included in the meta-analysis, of which 49 of the trials used a randomized process for allocating teeth with a certain material. Only studies that lasted at least two years were included in the analysis. No competing interests were found. In the Muller-Bolla study, 9 clinical reports directly compared light-cured resin-based sealants to fluoride-containing resin-based sealants, 5 of which were randomized clinical trials and 4 were controlled clinical trials. Follow up ranged from 8 months to 54 months.
Applicability The results are applicable to patients needing pit and fissure sealants. Authors of the Muller-Bola study determined that not only do FRBS have a lower long-term retention rate than LRBS, but also that multiple clinical reports show that the fluoride release is not significant enough to provide any clinical benefit.
Specialty/Discipline (Public Health) (General Dentistry) (Pediatric Dentistry)
Keywords pit and fissure sealant, fluoride, retention
ID# 2442
Date of submission: 04/01/2013spacer
E-mail allahdina@livemail.uthscsa.edu
Author Karim Allahdina
Co-author(s)
Co-author(s) e-mail
Faculty mentor/Co-author Joseph Connor, DDS
Faculty mentor/Co-author e-mail connorj@uthscsa.edu
Basic Science Rationale
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