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Title |
Articane Provides Longer Lasting Anesthesia in Buccal Infiltration Compared to Lidocaine on Healthy Teeth |
Clinical Question |
In a patient undergoing buccal infiltration is articaine longer lasting compared to lidocane on healthy teeth? |
Clinical Bottom Line |
For patients undergoing buccal infiltration, articane is longer lasting than lidocaine. This is supported by a meta-analysis in which articaine outperformed lidocaine by a clinically significant margin.
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Best Evidence |
(you may view more info by clicking on the PubMed ID link) |
PubMed ID |
Author / Year |
Patient Group |
Study type
(level of evidence) |
#1) 21531931 | Brandt/2011 | 13 studies (269 patients) | Meta-Analysis | Key results | Articaine 4% 1:100,000 epi proves to be 3.81 times longer lasting in buccal infiltration on healthy teeth than lidocaine 2% 1:100,000 epi with a 95% Cl. | |
Evidence Search |
(("Carticaine"[Mesh]) AND "Lidocaine"[Mesh]) AND "Anesthesia"[Mesh] |
Comments on
The Evidence |
Brandt and colleagues analyzed a set of randomized controlled trials and systematic reviews, with a total of 269 patients, comparing anesthetic length of both articaine 4% 1:100,000 epi and lidocaine 2% 1:100,000 epi. Lidocaine was used as the gold standard. Compilation of the article titles was done electronically, which resulted in elimination of any source of bias.
The qualities of all trials chosen were evaluated by considering randomization, and both description and number of patient losses.
No competing interests were found. |
Applicability |
Due to articaine‘s extensive availability and its similar price to lidocaine, it presents itself as a practical option for routine dental practices. However, its effect on inflamed teeth has not been proven. |
Specialty/Discipline |
(General Dentistry) |
Keywords |
Articaine, Lidocaine, Anesthesia.
|
ID# |
2437 |
Date of submission: |
03/01/2013 |
E-mail |
benavidesr@livemail.uthscsa.edu |
Author |
Roberto Benavides |
Co-author(s) |
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Co-author(s) e-mail |
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Faculty mentor/Co-author |
John Gildersleeve, DDS |
Faculty mentor/Co-author e-mail |
gildersleev@uthscsa.edu |
Basic Science Rationale
(Mechanisms that may account for and/or explain the clinical question, i.e. is the answer to the clinical question consistent with basic biological, physical and/or behavioral science principles, laws and research?) |
post a rationale |
None available | |
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Comments and Evidence-Based Updates on the CAT
(FOR PRACTICING DENTISTS', FACULTY, RESIDENTS and/or STUDENTS COMMENTS ON PUBLISHED CATs) |
post a comment |
None available | |
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