ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM
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Title Antibacterial Composite Resins Show Potential For Minimizing Secondary Caries
Clinical Question For patients needing composite resin restorations are antibacterial composites superior to traditional composites in preventing secondary caries?
Clinical Bottom Line Antibacterial composite resins show potential to reduce plaque accumulation, reducing secondary caries but more RCT need to be done.
Best Evidence (you may view more info by clicking on the PubMed ID link)
PubMed ID Author / Year Patient Group Study type
(level of evidence)
#1) 20379030Saku/20101 Male + 2 female In Situ
Key resultsIn comparison of Beautiful II, Clearfil, and Filtek there was no significant difference in antibacterial effect of the three. However, Beautiful II showed lower adhesion of plaque orally and lower quantity of S. mutans when soaked in human saliva in comparison with the other two composite resins.
#2) 19588443Pereira-Cenci/2009128 studies selected for review after database searchSystematic Review
Key resultsOf the 128 studies retrieved none met the selection criteria and more high level studies need to be conducted.
Evidence Search ("Composite Resins"[Mesh] AND ("Anti-Bacterial Agents"[Mesh] OR "Anti-Bacterial Agents"[Pharmacological Action])) AND "Dental Caries"[Mesh]
Comments on
The Evidence
The Meta-analysis was unable to identify any randomized controlled trials on the effects of antibacterial agents incorporated into composite restorations for the prevention of dental caries. The in situ study was done one year after the systematic review and is highest level of study we could find to date. There is a need for more High level clinical trials to be conducted.
Applicability Based on the evidence currently available the use of antibacterial composite resins does not provide indication that they are superior to existing composite resins. However, the idea of incorporating antibacterial agents should not be disregarded at this time so that further study the potential effects and benefits can be better understood of antibacterial composites.
Specialty/Discipline (Restorative Dentistry)
Keywords Antibacterial, Composite resin, caries
ID# 2407
Date of submission: 03/21/2013spacer
E-mail Simonra@livemail.uthscsa.edu
Author Robert Simon
Co-author(s)
Co-author(s) e-mail
Faculty mentor/Co-author Rita Renee Parma, DDS
Faculty mentor/Co-author e-mail PARMA@uthscsa.edu
Basic Science Rationale
(Mechanisms that may account for and/or explain the clinical question, i.e. is the answer to the clinical question consistent with basic biological, physical and/or behavioral science principles, laws and research?)
post a rationale
None available
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Comments on the CAT
(FOR PRACTICING DENTISTS' and/or FACULTY COMMENTS ON PUBLISHED CATs)
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None available
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