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Title |
Improvement Seen in Socket Preservation And Bone Resorption In Post Extraction Patients Treated With Bovine Bone Mineral And Porcine Collagen |
Clinical Question |
Is bone resorption and socket preservation improved in post-extraction patients treated with bovine bone mineral and porcine collagen compared to extraction alone in patients wanting implants? |
Clinical Bottom Line |
The use of bovine bone mineral and porcine collagen membrane decreases bone resorption compared to extraction alone. |
Best Evidence |
(you may view more info by clicking on the PubMed ID link) |
PubMed ID |
Author / Year |
Patient Group |
Study type
(level of evidence) |
#1) 22577648 | Cardaropoli/2012 | 41 Post Extraction Patients | Randomized Controlled Trial | Key results | There was less reduction in ridge width in the SP group (1.04 ± 1.08 mm vs 4.48 ± 0.65 mm, P < .001) and height (0.46 ± 0.46 mm vs 1.54 ± 0.33 mm, P < .001). Histologically, there was bone formation and maturation without inflammation. No significant difference in the mineralized and non-mineralized fractions was noted between the SP and control group. | |
Evidence Search |
"Bone matrix" [mesh] AND "Tooth Extraction"[mesh] AND "Regeneration" [mesh] |
Comments on
The Evidence |
This was a randomized controlled trial that included 41 patients who had one or more mandibular or maxillary molar or premolar extracted. The edentulous sites were randomly assigned to the experimental group (SP) or control group (EXT). The sockets were filled with bovine bone material and porcine collagen while the control group underwent extraction alone. The pocket probing depth, clinical attachment level, changes in residual ridge and histology were compared at baseline and after 4 months. All of patients completed the study and an adequate follow up was provided in order to compare residual ridge height, histology, PPD, and CAL. |
Applicability |
Patients wanting successful implants post extraction |
Specialty/Discipline |
(General Dentistry) (Oral Surgery) (Prosthodontics) |
Keywords |
Socket preservation, Bone transplantation, Collagen, Regeneration
|
ID# |
2386 |
Date of submission: |
03/08/2013 |
E-mail |
Maredia@livemail.uthscsa.edu |
Author |
Irena Maredia |
Co-author(s) |
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Co-author(s) e-mail |
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Faculty mentor/Co-author |
Gregory K. Spackman, DDS, MBA |
Faculty mentor/Co-author e-mail |
spackman@uthscsa.edu |
Basic Science Rationale
(Mechanisms that may account for and/or explain the clinical question, i.e. is the answer to the clinical question consistent with basic biological, physical and/or behavioral science principles, laws and research?) |
post a rationale |
None available | |
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Comments and Evidence-Based Updates on the CAT
(FOR PRACTICING DENTISTS', FACULTY, RESIDENTS and/or STUDENTS COMMENTS ON PUBLISHED CATs) |
post a comment |
None available | |
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