ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM
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Title Topical Administration of Diclofenac is as Effective as Systemic Administration in Alleviating Ailments of Temporomandibular Joint Disorder
Clinical Question In a patient suffering from Temporomandibular Joint Disorder, is topical administration of treatment as effective when compared to systemic administration of treatment in alleviating ailments?
Clinical Bottom Line Topical administration of diclofenac is as effective as systemic administration in alleviating ailments of temporomandibular joint disorder.
Best Evidence (you may view more info by clicking on the PubMed ID link)
PubMed ID Author / Year Patient Group Study type
(level of evidence)
#1) 15871609Di Rienzo/200436 adult patients diagnosed with dysfunction of the TMJRCT
Key resultsTopical administration of diclofenac was as effective as systemic administration in treatment of temporomandibular joint disorder syndromes with no significant difference (p < 0.05) based on reported VAS scores.
Evidence Search ("Temporomandibular Joint Disorders"[Mesh]) AND "Diclofenac"[Mesh]
Comments on
The Evidence
Only 1 relevant article available and the article is a RCT which is near the top of the evidence pyramid.
Applicability From the available evidence, it appears beneficial for patients to receive topical treatments for relief of syndromes associated with temporomandibular joint disorder as an alternative to systemic treatment.
Specialty/Discipline (General Dentistry)
Keywords Temporomandibular joint, temporomandibular disorders, topical treatment, systemic treatment, diclofenac, drug therapy, TMD therapy
ID# 2225
Date of submission: 04/13/2012spacer
E-mail pickei@livemail.uthscsa.edu
Author Ross Pickei
Co-author(s)
Co-author(s) e-mail
Faculty mentor/Co-author Edward F. Wright, DDS, MS
Faculty mentor/Co-author e-mail WRIGHTE2@UTHSCSA.EDU
Basic Science Rationale
(Mechanisms that may account for and/or explain the clinical question, i.e. is the answer to the clinical question consistent with basic biological, physical and/or behavioral science principles, laws and research?)
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None available
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Comments on the CAT
(FOR PRACTICING DENTISTS' and/or FACULTY COMMENTS ON PUBLISHED CATs)
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