Title Dental Implants May Be Considered In A Young Patient with Ectodermal Dysplasia
Clinical Question When would be the most appropriate time to place dental implants for patients with ectodermal dysplasia?
Clinical Bottom Line Although more evidence is needed, current case reports suggest dental implants can be placed in patients at a young age.
Best Evidence  
PubMed ID Author / Year Patient Group Study type
(level of evidence)
26418841Kilic/20156 year-old (followed for 6 years)Case report
Key resultsDuring the 6 years of follow up, there was no resorption of the bone around the implant area.
19548409Yap/2009Patients with ectodermal dysplasiaSystematic review of non-randomized trials
Key resultsImplants placement in patients with Ectodermal Dysplasia had a success rate in the range of 88.5-100%. Implants placed in patients younger then 18 years old compared to those who are older then 18 had higher risk of failure with a hazard ratio of 2.5.
10442937Kearns/19996 patients with ectodermal dysplasia (5-17 year-old)Cohort study
Key results97% of 41 implants integrated. Implants placed adjacent to an erupting natural tooth in a growing child became submerged by increased alveolar bone height.
Evidence Search (("ectodermal dysplasia"[MeSH Terms] OR ("ectodermal"[All Fields] AND "dysplasia"[All Fields]) OR "ectodermal dysplasia"[All Fields]) AND ("dental implants"[MeSH Terms] OR ("dental"[All Fields] AND "implants"[All Fields]) OR "dental implants"[All Fields] OR ("dental"[All Fields] AND "implant"[All Fields]) OR "dental implant"[All Fields])) AND systematic[sb]
Comments on
The Evidence
The articles were mostly limited in information. They followed patients who had implants placed at a young age for a period of time. Recall of most cases was successful since patients were young and parents were involved in the recall process. Study design did not allow for statistical comparisons. A comparison of osseointegration between different ages would be helpful as well as the risks and benefits may be different across ages.
Applicability When treatment planning for a patient with ectodermal dysplasia, it is important to consider a dental implant option. Height and width of alveolar bone, timing of dental implants, and osseointegration should be considered when evaluating for a patient with ectodermal dysplasia. Most articles raise the concern that children are still growing, which may affect dental implant success and function. However, it is also important to consider for children with this condition that the absence of teeth and abnormal teeth can affect their eating, appearance, and psycho-social well-being. Evidence from this aspect of implant therapy for these patients is lacking. In summary, dental implants may be placed in patients at a young age, but it is important to consider both the relative advantages and disadvantages for each patient given the limited evidence available to guide these decisions.
Specialty (Periodontics)
Keywords Ectodermal dysplasia, dental implants
ID# 3065
Date of submission 04/03/2016
E-mail Nguyenj9@livemail.uthscsa.edu
Author Jeanny Nguyen
Co-author(s)
Co-author(s) e-mail
Faculty mentor Thomas Oates, DMD, PhD
Faculty mentor e-mail Oates@uthscsa.edu
   
Basic Science Rationale
(Mechanisms that may account for and/or explain the clinical question, i.e. is the answer to the clinical question consistent with basic biological, physical and/or behavioral science principles, laws and research?)
None available
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Comments and Evidence-Based Updates on the CAT
(FOR PRACTICING DENTISTS', FACULTY, RESIDENTS and/or STUDENTS COMMENTS ON PUBLISHED CATs)
None available