Title Cyanoacrylate Stabilizers in Free Gingival Grafts
Clinical Question For patients undergoing soft tissue grafting to increase the width of keratinized tissue, does the use of a cyanoacrylate stabilizer improve the clinical outcomes for free gingival grafts when compared to conventional stabilization techniques?
Clinical Bottom Line For patients undergoing soft tissue grafting to increase the width of keratinized tissue, the use of a cyanoacrylate stabilizer does improve the clinical outcomes for free gingival grafts when compared to conventional stabilization techniques. This is supported by a randomized clinical trial in which the use of cyanoacrylate stabilizers led to significantly less surgery time, gingival graft shrinkage, and pain (p < 0.05 for each) when compared to conventional stabilization techniques and microsurgery techniques. The use of cyanoacrylate stabilizers is within the capability of the average general dental practice and is likely to be accepted by the average patient.
Best Evidence  
PubMed ID Author / Year Patient Group Study type
(level of evidence)
24494804Gumus/201445 Adult patients Randomized Controlled Trial
Key resultsAll subjects had less than 1 mm of attached gingiva on at least one mandibular anterior tooth with Miller Class III-IV recession. The use of cyanoacrylate stabilizers provided significantly less surgery time, gingival graft shrinkage, and pain (p < 0.05 for each) when compared to conventional stabilization techniques and microsurgery techniques.
Evidence Search ("transplants"[MeSH Terms] OR "transplants"[All Fields] OR "graft"[All Fields]) AND stabilization[All Fields] AND ("cyanoacrylates"[MeSH Terms] OR "cyanoacrylates"[All Fields] OR "cyanoacrylate"[All Fields])
Comments on
The Evidence
Validity: The study design was a randomized controlled trial. The groups were similar at start, had a greater than 80% completion rate, were treated the same, and had adequate follow up. This study was double blind and had adequate compliance. Recall bias was unlikely, and investigators had no competing interests.
Applicability The subjects used in this study are representative of those in general practice and in a periodontics practice, and the treatment is feasible in their respective settings. The patient’s potential benefits include decreased pain, surgery time, and free gingival graft shrinkage, and there are no apparent harms of using a cyanoacrylate stabilizer compared to conventional techniques. The patient’s value and expectations of treatment, including decreased pain, surgery time, and overall success of surgery, can be increased using the method in this study.
Specialty (General Dentistry) (Oral Surgery) (Periodontics)
Keywords free gingival graft, cyanoacrylate stabilizer, soft tissue graft, stabilization techniques
ID# 2870
Date of submission 04/01/2015
E-mail millert4@livemail.uthscsa.edu
Author Travis Miller
Co-author(s)
Co-author(s) e-mail
Faculty mentor Thomas Oates, DMD, PhD
Faculty mentor e-mail oates@uthscsa.edu
   
Basic Science Rationale
(Mechanisms that may account for and/or explain the clinical question, i.e. is the answer to the clinical question consistent with basic biological, physical and/or behavioral science principles, laws and research?)
None available
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Comments and Evidence-Based Updates on the CAT
(FOR PRACTICING DENTISTS', FACULTY, RESIDENTS and/or STUDENTS COMMENTS ON PUBLISHED CATs)
None available