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Title Dental Implants Are Successful In Patients With Osteogenesis Imperfecta
Clinical Question In patients with osteogenesis imperfecta (OI), how long will an implant supported dental prosthesis last without complications?
Clinical Bottom Line Patients with OI have a decreased quality of bone. The bone tends to be much softer than normal bone (most similar to type III). The survival of implants placed in type III bone is reported to be 50% (Misch), so we should be able to expect a 50% success rate for implants placed in patients with OI. Due to the bone quality when placing implants for OI patients consider using implants with features to improve initial stability and bone surface contact.
Best Evidence (you may view more info by clicking on the PubMed ID link)
PubMed ID Author / Year Patient Group Study type
(level of evidence)
#1) 14752964Lee/ 200343-year-old Asian woman with Type III OICase report/ lit review
Key resultsA block ramus graft was placed to augment the ridge laterally in the area of #28-32. Two implants were placed, and at the time of surgery the bone quality was noted to be very soft (type III). Two custom abutments were attached and a FDP (#29-31) cemented. At 2 years post prosthetic loading no pathology was noted, and the prosthesis is in full function.
#2) 17321445Prabhu/ 200732-year-old male with Type IV OICase Report
Key results11 implants were placed (6 Maxillary, 5 Mandibular), one maxillary implant was lost 6 months after placement but prior to prosthetic restoration. Fixed removable restorations were fabricated for the Max and Man arches. At 9 years post prosthetic loading 10 of the 11 implants were in function and showed no evidence of bone loss or pathology.
#3) 10759129Zola/ 200025-year-old white man with OICase Report
Key resultsIn 1990, 5 implants-(2 maxillary posterior, 3 mandibular posterior) were inserted. In 1992, 8 (4 maxillary & 4 mandibular) were inserted, and a sinus lift was completed. In 1996, 2 implants from those placed in 1992 failed (1 max, 1 Man). In 1997, another Max implant was lost, but it was replaced and referred back to the prosthodontist for restoration. No follow-up after pros restorations.
Evidence Search Search (osteogenesis imperfecta) AND dental implant Search (#13) AND dental implantsSearch osteogenesis imperfectaSearch "Dental Implants"[Mesh]
Comments on
The Evidence
The treatment of Osteogenesis Imperfecta patients with dental implants is very sparsely documented and needs more research. The area is at the earliest level of research, with only case reports in the literature at this time.
Applicability The evidence is applicable to patients with various types of OI who are missing teeth that could be replaced with dental implants.
Specialty/Discipline (General Dentistry) (Oral Surgery) (Pediatric Dentistry) (Periodontics) (Prosthodontics) (Restorative Dentistry)
Keywords Osteogenesis Imperfecta, Dental Implants, Sinus grafting
ID# 863
Date of submission: 05/05/2011spacer
E-mail masonag@livemail.uthscsa.edu
Author Amy Mason
Co-author(s) e-mail
Faculty mentor/Co-author Peter T. Gakunga, BDS, MS, PhD
Faculty mentor/Co-author e-mail GAKUNGA@uthscsa.edu
Basic Science Rationale
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None available
Comments and Evidence-Based Updates on the CAT
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by Elio Male & Sam Asthana (San Antonio, Texas) on 11/28/2017
by Elio Male & Sam Asthama (San Antonio, Texas) on 05/28/2017) This CAT addressed the success of dental implants in patients with osteogenesis imperfecta (OI). A new search was conducted in PubMed in November 2017. A more recent article, PMID 23484169, was published in 2013 by Friberg and further supports this CAT. This was a case report with a similar length of follow-up; the OI patient did not have complications with their dental implant.

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