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Title Implant Therapy In Children With Hypohidrotic Ectodermal Dysplasia Does Not Have A Significant Effect On Craniofacial Growth
Clinical Question In young dental patients with ectodermal dysplasia will treatment with implant therapy positively affect craniofacial development more than no treatment?
Clinical Bottom Line Current evidence is insufficient to decide whether treating children with ectodermal dysplasia with implants and subsequent prosthodontic therapy would positively impact craniofacial growth or if treatment should be delayed. (See Comments on the CAT below)
Best Evidence (you may view more info by clicking on the PubMed ID link)
PubMed ID Author / Year Patient Group Study type
(level of evidence)
#1) 19548409Yap/2009Patients with ectodermal dysplasia treated with dental implantsReview of Literature
Key resultsImplants placed in adolescent ED patients do not have a significant effect on craniofacial growth. Implants placed in ED patients younger than 18 years have a higher risk of failure. (The following article was referenced in this article.)
#2) 12376932Johnson/200250 children with untreated ED and 45 children treated with implants and 128 children in the non-ED groupCase Control
Key resultsCraniofacial morphology and growth did not differ significantly between implant-treated and non-treated ED children.
Evidence Search Search "Dental Prosthesis, Implant-Supported"[Mesh] Search "Dental Implantation"[Mesh] Search "Dental Implants"[Mesh] Search "Ectodermal Dysplasia"[Mesh]
Comments on
The Evidence
The evidence searched for this topic was found to be minimal. There are some case studies and very few reviews that accurately portray the results in the literature. This study compared ectodermal dysplasia patients treated with implants to those left untreated and to “normal” subjects (controlled), and followed them over time (longitudinal). For the literature available at this time, this study demonstrates good evidence.
Applicability In treatment planning for patients with ectodermal dysplasia, there are many things to take into account (i.e., growth and development of the craniofacial complex versus implant therapy at a wide range of ages). As prosthodontists, we need to know when it would be best to treat these patients and if fixed or removable appliances with or without implant therapy is indicated.
Specialty/Discipline (Prosthodontics)
Keywords Ectodermal dysplasia, craniofacial growth, implant therapy
ID# 773
Date of submission: 03/15/2011spacer
E-mail navazquez1208@yahoo.com
Author Nicole Vazquez
Co-author(s) e-mail
Faculty mentor/Co-author S. Thomas Deahl, II, DMD, PhD
Faculty mentor/Co-author e-mail DEAHL@uthscsa.edu
Basic Science Rationale
(Mechanisms that may account for and/or explain the clinical question, i.e. is the answer to the clinical question consistent with basic biological, physical and/or behavioral science principles, laws and research?)
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None available
Comments and Evidence-Based Updates on the CAT
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by Casey McGill, Briana Reinert, Alisha Hernandez (San Antonio, TX) on 01/06/2014
A PubMed search performed January 2014 found a Case Report and Review of Literature conducted by Kramer 2007, PubMed: 17224035 . Dental implants were successfully placed in a 8 year old male with ectodermal dysplasia. The review of literature indicated that in children with congenital hypodontia, dental implants at an early age can improve patient’s emotional well-being and help to preserve alveolar bone structure in areas of absent dentition.

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