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Title |
Herbal mouthwash more effective than OTC mouthwash and may be as effective as chlorhexidine rinse |
Clinical Question |
Can herbal mouthwash be as effective as OTC mouthwash at preventing gum disease? |
Clinical Bottom Line |
In vivo, both herbal mouth and gum therapy and Peridex were significantly more effective at inhibiting microbial growth than Listerine. In vitro, Chlorhexidine rinse was the most effective; herbal rinse was less effective than chlorhexidine but more effective than an essential oil rinse. (See Comments on the CAT below) |
Best Evidence |
(you may view more info by clicking on the PubMed ID link) |
PubMed ID |
Author / Year |
Patient Group |
Study type
(level of evidence) |
#1) 18451378 | Haffajee/2008 | 120 inoculated plates | In vitro study | Key results | In vitro, Chlorhexidine rinse was the most effective, herbal rinse was less effective than chlorhexidine but more effective than an essential oil rinse. | #2) 10518852 | Gultz/1998 | 20 humans | Comparative Study | Key results | In vivo, both Herbal mouth and gum therapy and Peridex were significantly more effective at inhibiting microbial growth than Listerine when grown in petri dishes. | #3) 10518858 | Scherer/1998 | 40 humans | Randomized Controlled Trial | Key results | Herbal mouth and gum therapy significantly decreased bleeding on probing and gingivitis compared to water used as a control (ANOVA p<0.01). | |
Evidence Search |
Herbal Mouth and Gum Therapy;[Substance Name] |
Comments on
The Evidence |
In vivo studies need to be done to confirm or dispute the data from the in vitro study in 2008. Also, long term follow-up should be conducted. The amount of significance in the Gultz article is not noted and should have been. |
Applicability |
Any patient looking for alternatives to traditional mouthwash. |
Specialty/Discipline |
(Public Health) (Periodontics) (Dental Hygiene) |
Keywords |
Chlorhexidine, mouthwash, herbal mouthwash, essential oil, peridex
|
ID# |
479 |
Date of submission: |
01/08/2010 |
E-mail |
cooperrb@uthscsa.edu |
Author |
R. Bryn Cooper |
Co-author(s) |
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Co-author(s) e-mail |
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Faculty mentor/Co-author |
Barbara MacNeill, DMD |
Faculty mentor/Co-author e-mail |
macneill@uthscsa.edu |
Basic Science Rationale
(Mechanisms that may account for and/or explain the clinical question, i.e. is the answer to the clinical question consistent with basic biological, physical and/or behavioral science principles, laws and research?) |
post a rationale |
None available | |
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Comments and Evidence-Based Updates on the CAT
(FOR PRACTICING DENTISTS', FACULTY, RESIDENTS and/or STUDENTS COMMENTS ON PUBLISHED CATs) |
post a comment |
by Kristi Johnson (San Antonio, Texas) on 04/09/2012 I conducted a PubMed search on this topic on April 9, 2012 and found contradictory findings in a recent publication: PMID 16451766. This RCT of 63 patients studied the effect of chlorhexidine, herbal mouth rinse, and a placebo, and found that CHX was the only rinse to have a statistically significant effect on gingival index, plaque index, and bleeding on probing. The herbal mouth rinse did not have a statistically significant effect on any of these measures. | |
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