ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM
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Title Mineral Trioxide Aggregate (MTA) is a Good Alternative Wound Dressing Than Formocresol (FC) for Pulpotomies in Primary Teeth
Clinical Question Does MTA work as effectively as a pulpal medicament as FC in pulpotomies of primary molars?
Clinical Bottom Line MTA is a good alternative treatment to FC for pulpotomies in primary teeth with lower failure rates less internal root resorption. (See Comments on the CAT below)
Best Evidence (you may view more info by clicking on the PubMed ID link)
PubMed ID Author / Year Patient Group Study type
(level of evidence)
#1) 17138165Peng/20066 StudiesMeta-analysis
Key resultsMTA versus FC pulpotomy suggested that MTA was superior to FC in pulpotomy resulting in a lower failure rate, with the RR (Relative Risk) being 0.32 (95% confidence interval [CI] 0.11 to 0.90) and 0.31 (95% CI 0.13 to 0.74), respectively. Internal root resorption happened less in the MTA group with RR 0.29, 95% CI 0.11 to 0.77." quoted from Abstract
Evidence Search "formocresol" [Supplementary Concept]) AND "mineral trioxide aggregate" [Supplementary Concept] AND “Pulpotomy”[Mesh] ...view in PubMed
Comments on
The Evidence
The highest level of evidence (Meta-analysis) demonstrated improved treatment outcome when using MTA wound dressing compared with FC.
Applicability Inclusion criteria for reviewed studies specified that “all teeth were primary molar teeth with exposure of vital pulp by caries or trauma, with no internal root resorption, interradicular and periapical bone destruction, periodontium involvement, swelling, nor sinus tract, [and that] all teeth would be restorable with posterior stainless steel crowns.”
Specialty/Discipline (Public Health) (Endodontics) (General Dentistry) (Pediatric Dentistry) (Restorative Dentistry)
Keywords FERRIC SULFATE; FORMOCRESOL; MINERAL TRIOXIDE AGGREGATE; PRIMARY TEETH; PULP THERAPY
ID# 471
Date of submission: 01/06/2010spacer Revised: 08/16/2011
E-mail cooperrb@uthscsa.edu
Author Rachel Foster
Co-author(s) R. Bryn Cooper
Co-author(s) e-mail
Faculty mentor/Co-author Lina M. Cardenas, DDS
Faculty mentor/Co-author e-mail
Basic Science Rationale
(Mechanisms that may account for and/or explain the clinical question, i.e. is the answer to the clinical question consistent with basic biological, physical and/or behavioral science principles, laws and research?)
post a rationale
None available
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Comments and Evidence-Based Updates on the CAT
(FOR PRACTICING DENTISTS', FACULTY, RESIDENTS and/or STUDENTS COMMENTS ON PUBLISHED CATs)
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by Luciana Torres (San Antonio,TX) on 04/08/2012
I conducted a Pubmed search on this topic, April 2012. A more recent publication was found: Pubmed ID:18534173. This meta analaysis included 18 RCTs and 10 CTs totaling in 1260 molars that compared MTA and FC. The results of the study further strengthens the conclusion of this CAT.
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