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Title | Pharmacological Dental Anxiety Management with Ketamine and Midazolam in Uncooperative Children | ||||||||||||
Clinical Question | In young uncooperative children, will ketamine be more effective than midazolam in reducing dental anxiety? | ||||||||||||
Clinical Bottom Line | The benzodiazepine midazolam was more effective than ketamine in reducing dental anxiety in young uncooperative children. (See Comments on the CAT below) | ||||||||||||
Best Evidence | (you may view more info by clicking on the PubMed ID link) | ||||||||||||
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Evidence Search | Limits: Systematic Reviews Randomized Controlled Trial, Systematic Reviews Meta-Analysis\"Midazolam"Ketamine"[Mesh] \"Benzodiazepines"[Mesh] Dental Anxiety" | ||||||||||||
Comments on The Evidence |
The study was double blind and randomized with adequate follow-up and compliance. The weaknesses are that it was a small study (10 subjects per group) with a lack of a placebo group. | ||||||||||||
Applicability | Oral sedation will be more accepted by parents and patients. The fact that there will be fewer side effects with the use of midazolam is an added benefit that pediatric dentists can use to their advantage in gaining informed consent from a child patient’s parents. Children and thus parents will be less traumatized by procedures performed at the pediatric dentists' office. | ||||||||||||
Specialty/Discipline | (Pediatric Dentistry) (Behavioral Science) | ||||||||||||
Keywords | Dental anxiety; Midazolam; Ketamine |
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ID# | 447 | ||||||||||||
Date of submission: | 12/08/2009 | ||||||||||||
aworinde@livemail.uthscsa.edu | |||||||||||||
Author | Adepeju Aworinde | ||||||||||||
Co-author(s) | Steven Hogan | ||||||||||||
Co-author(s) e-mail | hoganS@uthscsa.edu | ||||||||||||
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