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| Title |
The Supplemental Use of Chlorhexidine with Scaling and Root Planning Therapy, When Treating Diabetic Patients, does not Significantly Improve Periodontal Outcomes as Compared to Scaling and Root Planning Alone |
| Clinical Question |
For diabetic patients undergoing scaling and root planning periodontal therapy, does a combination therapy that includes Chlorhexidine significantly improve periodontal outcomes over scaling and root planning without chlorhexidine? |
| Clinical Bottom Line |
The use of Chlorhexidene in a combination therapy did not yield statistically significant results when compared to scaling and root planning therapy alone. |
| Best Evidence |
(you may view more info by clicking on the PubMed ID link) |
| PubMed ID |
Author / Year |
Patient Group |
Study type
(level of evidence) |
| #1) 23305133 | Santos/2013 | Subjects with poorly controlled type 2 diabetes and generalized chronic periodontitis. | Randomized Controlled Trial | | Key results | All clinical parameters, with and without chlorhexidine, improved at all time post-therapies markers for both groups (p < 0.05). There were no significant differences between groups for any clinical parameters, and glycemic condition at any time-point (p > 0.05). | |
| Evidence Search |
(“Diabetes Mellitus”[MeSH] AND “ Periodontitis”[All Fields] AND “chlorhexidine “All Fields]) |
Comments on
The Evidence |
The randomized controlled clinical trial added chlorhexidine to its trials to test its efficacy. There is a need to conduct more studies among diabetic patients that show a greater numerical change in outcomes with a larger sample size to adequately observe a statistically significant change in diabetes glycemic parameters and periodontal disease.
|
| Applicability |
The benefits of adding chlorhexidine to scaling and root planning therapy are not statistically significant enough to include it to the diabetic patient’s periodontal disease treatment. |
| Specialty/Discipline |
(Public Health) (General Dentistry) (Periodontics) (Dental Hygiene) |
| Keywords |
Diabetes Mellitus, Chlorhexidine, Periodontal Therapy
|
| ID# |
2628 |
| Date of submission: |
03/28/2014 |
| E-mail |
Hemmat@livemail.uthscsa.edu |
| Author |
Peggah Hemmat |
| Co-author(s) |
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| Co-author(s) e-mail |
|
| Faculty mentor/Co-author |
Juanita Lozano-Pineda, DDS, MPH |
| Faculty mentor/Co-author e-mail |
Pinedaj@uthscsa.edu |
Basic Science Rationale
(Mechanisms that may account for and/or explain the clinical question, i.e. is the answer to the clinical question consistent with basic biological, physical and/or behavioral science principles, laws and research?) |
post a rationale |
| None available | |
|
Comments and Evidence-Based Updates on the CAT
(FOR PRACTICING DENTISTS', FACULTY, RESIDENTS and/or STUDENTS COMMENTS ON PUBLISHED CATs) |
post a comment |
| None available | |
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