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Title Soft Tissue Profile Changes Occur From Late Adolescence To Late Adulthood In Persons With No History Of Orthodontic Therapy
Clinical Question Does the soft tissue profile change from late adolescence to late adulthood in persons with no history of orthodontic therapy?
Clinical Bottom Line Several changes observed in the soft tissue profile from late adolescence to late adulthood were noted as significant.
Best Evidence (you may view more info by clicking on the PubMed ID link)
PubMed ID Author / Year Patient Group Study type
(level of evidence)
#1) 18929267Pecora / 200839 adolescent humans followed to late adulthood Prospective Clinical study
Key resultsSeveral soft tissue profile features showed statistically significance change from late adolescence to late adulthood. The upper lip length increased by 4.6 mm, upper lip thickness decreased by 5 mm, soft tissue thickness at pogonion increased by 1.2 mm, and the nasal tip and columella drooped by 2.9 and 2.7 mm, respectively. All listed changes demonstrated a p-value <0.01.
Evidence Search ((("Humans"[MeSH Terms]) AND "Longitudinal Studies"[MeSH Terms]) AND "Cephalometry/statistics and numerical data"[MeSH Terms]) AND "Aging"[MAJR]
Comments on
The Evidence
This was an uncontrolled prospective clinical study of 39 orthodontically untreated subjects from the University of Michigan Elementary and Secondary School Growth Study in which a cephalometric radiograph was taken at ages 17.4 +/- 0.7, 46 +/- 3.3, and 57.2 +/- 3.5 years for 19 men, and at 17.2 +/- 0.8, 47.5 +/- 3.4, 58.5 +/- 3.7 years for 20 women to evaluate both soft tissue and skeletal changes over time. Examiners were blinded to the identity of subjects.
Applicability Mean ages of the included subjects ranged from 17.2 to 58.5 years. Thirty-nine subjects with no history of orthodontic treatment participated in the study (19 men and 20 women). Ethnicity, dental health, or medical health of subjects could not be assessed.
Specialty/Discipline (Orthodontics)
Keywords Soft tissue profile, orthodontics, growth, maturation
ID# 2157
Date of submission: 10/07/2011spacer
E-mail parkerj4@uthscsa.edu
Author Joshua Parker
Co-author(s) e-mail
Faculty mentor/Co-author Clarence C. Bryk, DDS, MS
Faculty mentor/Co-author e-mail BRYKC@uthscsa.edu
Basic Science Rationale
(Mechanisms that may account for and/or explain the clinical question, i.e. is the answer to the clinical question consistent with basic biological, physical and/or behavioral science principles, laws and research?)
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None available
Comments and Evidence-Based Updates on the CAT
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by Jonathan Abay Jennifer La (San Antonio, TX) on 11/28/2017
A PubMed search was conducted in November 2017, and no recent research on the topic was found. Many articles explained the soft tissue profile changes with aging but not as they relate to a lack in orthodontic treatment. More studies over a long period of time are needed to show differences, if they exist, in soft tissue changes in patients with/without orthodontic treatment.

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